CBD for Anxiety: Effects | Research | Side Effects

CBD for Anxiety: Effects | Research | Side Effects

CBD for anxiety is becoming increasingly popular. But how does it work?

Cannabidiol (CBD) is one of many cannabinoids found in cannabis plants. It’s a non-psychoactive compound, which means that it won’t get you high. CBD is believed to have many positive health effects.

It’s often used by people who suffer from chronic pain, anxiety, and insomnia. CBD is thought to interact with the body’s endocannabinoid system, which supports homeostasis in the body.

This means that CBD can help keep your body running smoothly. But people seem to be most excited about CBD's potential to help them deal with anxiety.

This article explores how CBD may help reduce anxiety, and whether it could be a potential option for you.

CBD for Anxiety: Is it Effective?

A growing body of evidence from preclinical trials suggests that CBD may be helpful in treating anxiety. Preclinical studies explored the following anxiety related disorders:

  • OCD (obsessive compulsive disorder)
  • PTSD (post traumatic stress disorder)
  • Social anxiety disorder
  • Generalized anxiety disorder
  • Social anxiety disorder
  • Panic disorder

Some evidence suggests that CBD may have an anxiolytic role in acute doses. But few studies have looked at whether it can be used to effectively treat anxiety when taken chronically. In other words, for long periods of time or over the course of months.

The anxiolytic properties of CBD may be due to its ability to increase levels of anandamide, which is a cannabinoid neurotransmitter in the brain. Anandamide has been shown to reduce anxiety in animal studies when administered alone.

Other studies have found that CBD can reduce the effects of THC. This may be why users report less anxiety when using cannabis products that contain both CBD and THC.

The available evidence indicates that CBD could be a viable treatment for anxiety disorders. But more research is needed to determine long-term effects and how it works in different clinical populations.

Quick Recap: What is CBD?

What is CBD?

Cannabidiol is one of many chemical compounds found in cannabis plants. Unlike the most well-known compound, tetrahydrocannabinol (THC), cannabidiol does not cause a euphoric high.

Recently, there has been a surge of interest in the potential use of CBD as an anxiolytic treatment.

How Does CBD Work?

CBD, although it is not fully understood how it works in the body and brain, has been shown to have therapeutic properties in a number of conditions that affect mental health.

The human body contains many different protein-based chemical structures called receptors. Receptors receive signals from outside sources and send information to the cells they are attached to. These receptors are best understood as light switches, turning on or off, sending or receiving messages when certain stimuli attach themselves.

There are many different types of receptors, each responsible for receiving a specific type of signal. The two most well-known types are the cannabinoid receptors (CB1 and CB2) and the serotonin receptors (5-HT1A). These receptors format large network within the body known as the endocannabinoid system.

There is some evidence that CBD may interact with cannabinoid receptors, most importantly CB1 and CB2. CB1 is located in the central nervous system while CB2 is found in the peripheral nervous system.

The exact effects of CBD on CB1 receptors in the brain are not yet fully understood. However, it is known that CBD affects serotonin signaling pathways. Evidence suggests that CBD may interact with the 5-HT1A serotonin receptor in a manner similar to the way it interacts with cannabinoid receptors. The 5-HT1A receptor is found in many areas of the brain, including those associated with anxiety and depression.

Serotonin, a chemical produced by the brain that influences moods and behavior, is essential to emotional well-being. Low levels of the neurotransmitter serotonin are associated with depression and anxiety disorders.

Are there any prescription medications for low serotonin?

There are currently two prescription medications available:

  • Zoloft (sertraline)
  • Prozac (fluoxetine)

There are some people that use CBD to ease anxiety-related conditions, instead of prescription medications. Always consult with your doctor if you are considering using CBD for anxiety.

CBD Drinks to Help Manage Anxiety

CBD oil is one of the most popular products on the market. This is undeniable. But how efficient is it for dosing? Dropper bottles make it difficult to know exactly how many drops you're administering. But without bashing other products, let's discuss a simple and easy way to get your daily dose of CBD: CBD drinks.

CBD drinks are refreshing, hydrating, and easy to drink. They have a set amount of CBD per can or bottle, so there's no complications when it comes to dosing. This is the perfect way to get started on CBD by enabling you to experience an immediate, relaxing and non-intoxicating effect.


Product Spotlight: CBD Sparkling Water

Clean, refreshing, natural. That's our citrus-flavored sparkling water that helps you find your center.

Take a moment, take a sip. It's time to find your CENTR.

Each thirst quenching 12 oz. can contains:

  • 30mg CBD Isolate (hemp-derived)
  • 40 Calories (Sugar Free option has only 10 calories)
  • All Natural Ingredients
  • No THC | No Caffeine | No Alcohol


A CBD beverage is a pretty perfect way to sip your way to a soothing headspace. They're also made with all natural ingredients, so there's no nasty artificials in your sip. Take a look at CENTR's CBD drink products, and receive 10% off your first order today.

The Bottom Line: CBD for Anxiety

Many people are using CBD for treating anxiety disorders and other health concerns. Preclinical studies show conclusive evidence for CBD's potential in treating anxiety. But the emphasis remains on the word potential. This is because more controlled clinical trials need to take place, especially for long-term dosing. If you are thinking of using CBD for anxiety, first consult with your doctor before adjusting your current treatment plan.